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• Medical research >> Clinical Trials >> Mental health trials >> Fenella - Interview 20 >> Every trial has some risk, but medical research is carefully regulated to protect patient safety, and not all trials are about drugs.

Fenella took part in a randomised trial of partial hospitalisation compared to standard community treatment for borderline personality disorder. Results showed the group she was in (partial hospitalisation) had better outcomes.

• Medical research >> Clinical Trials >> Long term conditions >> Kate - Interview 13 >> There was a small risk from the injections of anaphylactic shock, but there were safety precautions in place. They kept a diary to report other reacti

Kate and her husband took part in a trial comparing injections of grass pollen antigen against a placebo as a way to reduce hay fever. Kate was in the experimental group and her husband in the placebo group.

• Medical research >> Clinical Trials >> Not taking part in a trial >> Marie - Interview 25 >> She had heard bad things about commercial trials. She thought a trial in an NHS hospital would be run by the NHS and was worried to discover it was ru

Marie was diagnosed with chronic lymphocytic leukaemia in 1992. She was recently invited to take part in a clinical trial of a new monoclonal antibody. At first she thought she would take part but after reading all the details decided against it.

• Medical research >> Clinical Trials >> Screening, prevention other medical interventions >> Leslie - Interview 43 >> Leslie thinks there is too much secrecy around drug company trials, and feels they are more interested in profit than safety.

Leslie took part in a placebo-controlled drug trial of rofecoxib (Vioxx) for prostate cancer prevention. He became extremely ill, but doctors monitoring his progress did not pick up his symptoms. He took the drug company to court, and won compensation.

• Medical research >> Clinical Trials >> Long term conditions >> Kate - Interview 13 >> There are strict regulations in place to protect patient safety, so the risk of something going seriously wrong in any trial is very small. Lessons ha

Kate and her husband took part in a trial comparing injections of grass pollen antigen against a placebo as a way to reduce hay fever. Kate was in the experimental group and her husband in the placebo group.

• Medical research >> Clinical Trials >> Organising trials >> Lester - Interview 06 >> Drug companies will of course research products in order to make money, but the UK has a good system of regulation. Lester is more worried about wheth

Lester’s son Ellis died in 2001 of variant CJD. Lester later became involved as a lay chair of a trial looking at the effectiveness of a drug called quinacrine for people with variant CJD.