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Clinical Trials
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Finding out about a trial :
What are clinical trials and why do we need them?
Different types of clinical trial
Being asked about taking part in a trial
Information and questions
Difficulties finding a trial to join
Deciding whether to take part – risk and benefits :
Reasons for wanting to take part – personal benefit
Reasons for wanting to take part – helping medical science
Deciding not to take part
Thinking about withdrawing from a trial
Why people may not be eligible to join a trial
Being in a trial :
Feelings about being allocated (randomised) to a treatment group
Feelings about being in a placebo-controlled trial
Blinded trials
Non-randomised trial designs and other studies
Side effects and queries
Time commitment, money and other practical issues
Appointments, monitoring, questionnaires
Communication between different health professionals
At the end of a trial :
Feelings when a trial ends
Feedback of trial results
Other issues :
Attitudes to taking part in another trial
Funding and publishing trials
Public awareness and involvement
Under-researched topics/priorities for other research
Messages to other people
Messages to professionals
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Clinical Trials
Subject index
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Medical research
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Clinical Trials
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Mental health trials
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Fenella - Interview 20
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Fenella describes a trial testing the effectiveness of a computerised behavioural therapy programme for managing anxiety disorders, compared to conven
Fenella took part in a randomised trial of partial hospitalisation compared to standard community treatment for borderline personality disorder. Results showed the group she was in (partial hospitalisation) had better outcomes.
Medical research
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Clinical Trials
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Mental health trials
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Anton - Interview 28
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Anton says nothing has helped his depression, and he is desperate to try anything. He hopes by taking part in trials he will one day find an effective
Anton has a long history of depression and has volunteered for several different trials in mental health, including trials of talking therapies as well as drug trials.
Medical research
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Clinical Trials
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Mental health trials
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Fenella - Interview 20
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Looking back, Fenella feels one benefit of being in the trial was having access to staff who were expert and motivated to find the very best treatment
Fenella took part in a randomised trial of partial hospitalisation compared to standard community treatment for borderline personality disorder. Results showed the group she was in (partial hospitalisation) had better outcomes.
Medical research
>>
Clinical Trials
>>
Mental health trials
>>
Fenella - Interview 20
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Fenella was given a copy of the journal article reporting the trial results. It was rewarding to feel her contribution had helped other people.
Fenella took part in a randomised trial of partial hospitalisation compared to standard community treatment for borderline personality disorder. Results showed the group she was in (partial hospitalisation) had better outcomes.
Medical research
>>
Clinical Trials
>>
Mental health trials
>>
Fenella - Interview 20
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Not all patients will be able to read an academic journal article, so other ways of presenting results must be found. During the trial, postcards coul
Fenella took part in a randomised trial of partial hospitalisation compared to standard community treatment for borderline personality disorder. Results showed the group she was in (partial hospitalisation) had better outcomes.
Medical research
>>
Clinical Trials
>>
Mental health trials
>>
Fenella - Interview 20
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Every trial has some risk, but medical research is carefully regulated to protect patient safety, and not all trials are about drugs.
Fenella took part in a randomised trial of partial hospitalisation compared to standard community treatment for borderline personality disorder. Results showed the group she was in (partial hospitalisation) had better outcomes.
Medical research
>>
Clinical Trials
>>
Mental health trials
>>
Fenella - Interview 20
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More mental health research is important, including into depression after a physical illness has been diagnosed, and into treatments which are not dru
Fenella took part in a randomised trial of partial hospitalisation compared to standard community treatment for borderline personality disorder. Results showed the group she was in (partial hospitalisation) had better outcomes.
Medical research
>>
Clinical Trials
>>
Mental health trials
>>
Fenella - Interview 20
>>
Fenella explains the trial treatment for borderline personality disorder and why questionnaires were important to check the effect on her mental state
Fenella took part in a randomised trial of partial hospitalisation compared to standard community treatment for borderline personality disorder. Results showed the group she was in (partial hospitalisation) had better outcomes.
Medical research
>>
Clinical Trials
>>
Mental health trials
>>
Fenella - Interview 20
>>
Fenella is now involved with her local Mental Health Research Network, and explains how she came up with a new research proposal.
Fenella took part in a randomised trial of partial hospitalisation compared to standard community treatment for borderline personality disorder. Results showed the group she was in (partial hospitalisation) had better outcomes.
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