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Clinical Trials
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Finding out about a trial :
What are clinical trials and why do we need them?
Different types of clinical trial
Being asked about taking part in a trial
Information and questions
Difficulties finding a trial to join
Deciding whether to take part – risk and benefits :
Reasons for wanting to take part – personal benefit
Reasons for wanting to take part – helping medical science
Deciding not to take part
Thinking about withdrawing from a trial
Why people may not be eligible to join a trial
Being in a trial :
Feelings about being allocated (randomised) to a treatment group
Feelings about being in a placebo-controlled trial
Blinded trials
Non-randomised trial designs and other studies
Side effects and queries
Time commitment, money and other practical issues
Appointments, monitoring, questionnaires
Communication between different health professionals
At the end of a trial :
Feelings when a trial ends
Feedback of trial results
Other issues :
Attitudes to taking part in another trial
Funding and publishing trials
Public awareness and involvement
Under-researched topics/priorities for other research
Messages to other people
Messages to professionals
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Clinical Trials
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Medical research
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Clinical Trials
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Trials involving surgery
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Alex - Interview 45
>>
Alex understood doctors were unsure whether to recommend surgery for heel fracture or not. He had a slight preference for surgery but random allocatio
Alex fractured his heel in 2007. He agreed to take part in a trial comparing surgery with letting the bones heal naturally. He was randomised to the group having surgery, and his heel is slowly recovering.
Medical research
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Clinical Trials
>>
Not taking part in a trial
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Lesley - Interview 44
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She felt this was a decision she had to make for herself. The research assistant accepted her decision and did not try to change her mind.
Lesley slipped and fractured her heel. She was invited to take part in a trial comparing surgery with letting the bones heal naturally. She decided not to take part because she wanted the consultant to make a decision about treatment.
Medical research
>>
Clinical Trials
>>
Trials involving surgery
>>
Alex - Interview 45
>>
Alex wonders if he got faster access to diagnostic tests because he’d agreed to be in the trial, but he thinks the quality of care overall was no diff
Alex fractured his heel in 2007. He agreed to take part in a trial comparing surgery with letting the bones heal naturally. He was randomised to the group having surgery, and his heel is slowly recovering.
Medical research
>>
Clinical Trials
>>
Trials involving surgery
>>
Alex - Interview 45
>>
It did not worry him that he might be allocated to have surgery – compared with other people around him on the ward his problems seemed minor and he w
Alex fractured his heel in 2007. He agreed to take part in a trial comparing surgery with letting the bones heal naturally. He was randomised to the group having surgery, and his heel is slowly recovering.
Medical research
>>
Clinical Trials
>>
Not taking part in a trial
>>
Lesley - Interview 44
>>
When Lesley fractured her heel, she wanted to be told by a doctor what to do. She felt being in the trial would make her responsible for choosing, eve
Lesley slipped and fractured her heel. She was invited to take part in a trial comparing surgery with letting the bones heal naturally. She decided not to take part because she wanted the consultant to make a decision about treatment.
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