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Clinical Trials
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Finding out about a trial :
What are clinical trials and why do we need them?
Different types of clinical trial
Being asked about taking part in a trial
Information and questions
Difficulties finding a trial to join
Deciding whether to take part – risk and benefits :
Reasons for wanting to take part – personal benefit
Reasons for wanting to take part – helping medical science
Deciding not to take part
Thinking about withdrawing from a trial
Why people may not be eligible to join a trial
Being in a trial :
Feelings about being allocated (randomised) to a treatment group
Feelings about being in a placebo-controlled trial
Blinded trials
Non-randomised trial designs and other studies
Side effects and queries
Time commitment, money and other practical issues
Appointments, monitoring, questionnaires
Communication between different health professionals
At the end of a trial :
Feelings when a trial ends
Feedback of trial results
Other issues :
Attitudes to taking part in another trial
Funding and publishing trials
Public awareness and involvement
Under-researched topics/priorities for other research
Messages to other people
Messages to professionals
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Clinical Trials
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Clinical Trials
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Long term conditions
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Kate - Interview 13
>>
There was a small risk from the injections of anaphylactic shock, but there were safety precautions in place. They kept a diary to report other reacti
Kate and her husband took part in a trial comparing injections of grass pollen antigen against a placebo as a way to reduce hay fever. Kate was in the experimental group and her husband in the placebo group.
Medical research
>>
Clinical Trials
>>
Long term conditions
>>
Kate - Interview 13
>>
Kate advises people to think carefully about the commitment involved before they agree. If you are going to pull out, do it as early as possible for t
Kate and her husband took part in a trial comparing injections of grass pollen antigen against a placebo as a way to reduce hay fever. Kate was in the experimental group and her husband in the placebo group.
Medical research
>>
Clinical Trials
>>
Long term conditions
>>
Kate - Interview 13
>>
Kate and her husband hoped a trial of grass pollen immunotherapy would improve their hay fever, and also help others in future. Free medication was an
Kate and her husband took part in a trial comparing injections of grass pollen antigen against a placebo as a way to reduce hay fever. Kate was in the experimental group and her husband in the placebo group.
Medical research
>>
Clinical Trials
>>
Long term conditions
>>
Kate - Interview 13
>>
Occasionally Kate and her husband found keeping appointments ‘a bit of a chore’, especially when he realised he must be in the placebo group, but they
Kate and her husband took part in a trial comparing injections of grass pollen antigen against a placebo as a way to reduce hay fever. Kate was in the experimental group and her husband in the placebo group.
Medical research
>>
Clinical Trials
>>
Long term conditions
>>
Kate - Interview 13
>>
Kate’s husband was annoyed when he guessed he was in the placebo group. He continued for the sake of the study, but it was a relief when it ended. He
Kate and her husband took part in a trial comparing injections of grass pollen antigen against a placebo as a way to reduce hay fever. Kate was in the experimental group and her husband in the placebo group.
Medical research
>>
Clinical Trials
>>
Long term conditions
>>
Kate - Interview 13
>>
Kate and her husband guessed correctly that she was getting the active injection and he was getting the placebo, because they reacted differently.
Kate and her husband took part in a trial comparing injections of grass pollen antigen against a placebo as a way to reduce hay fever. Kate was in the experimental group and her husband in the placebo group.
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