• Clip
• Medical research >> Clinical Trials >> Cancer drugs and radiotherapy - randomised trials >> Jayne - Interview 03 >> When Jayne learnt she had breast cancer in 1994, she knew it was unclear which treatment was best and asked to join a trial. The consultant was dismis

Jayne had breast cancer aged 33. She wanted to join a clinical trial but her consultant was not interested, so she transferred to another hospital and took part in a trial comparing tamoxifen with tamoxifen plus goserelin (Zoladex).

• Medical research >> Clinical Trials >> Screening, prevention other medical interventions >> Amanda - Interview 22 >> Amanda wanted to run a trial on herself to see if a change of drug made any real difference to her arthritis, but was held up by the ethics approval p

Amanda has taken part in a trial of pro-biotic yoghurt for irritable bowel syndrome, and withdrew from a trial about early interventions to prevent diabetes. She is setting up a website for the public to design their own trials.

• Medical research >> Clinical Trials >> Mental health trials >> Fenella - Interview 20 >> You can find information about research on the internet, from your local academic department, or your GP or specialist. She asks professionals, “If yo

Fenella took part in a randomised trial of partial hospitalisation compared to standard community treatment for borderline personality disorder. Results showed the group she was in (partial hospitalisation) had better outcomes.

• Medical research >> Clinical Trials >> Mental health trials >> Anton - Interview 28 >> Anton says nothing has helped his depression, and he is desperate to try anything. He hopes by taking part in trials he will one day find an effective

Anton has a long history of depression and has volunteered for several different trials in mental health, including trials of talking therapies as well as drug trials.

• Medical research >> Clinical Trials >> Cancer drugs and radiotherapy - randomised trials >> Jayne - Interview 03 >> Jayne is strongly committed to the value of research and wanted something good to come out of her illness – not for herself but for others, including

Jayne had breast cancer aged 33. She wanted to join a clinical trial but her consultant was not interested, so she transferred to another hospital and took part in a trial comparing tamoxifen with tamoxifen plus goserelin (Zoladex).

• Medical research >> Clinical Trials >> Not taking part in a trial >> Polly - Interview 09 >> Polly decided not to take part in a placebo-controlled trial of tamoxifen because she felt there was already enough evidence it worked for breast canc

Polly was invited to be in a trial comparing tamoxifen against a placebo for breast cancer in the 1990s. She decided not to take part, because she felt there was already good evidence to support the use of tamoxifen.

• Medical research >> Clinical Trials >> Screening, prevention other medical interventions >> Amanda - Interview 22 >> Amanda’s main motivation is to contribute to medical knowledge and test whether there really is evidence for treatments we assume are effective.

Amanda has taken part in a trial of pro-biotic yoghurt for irritable bowel syndrome, and withdrew from a trial about early interventions to prevent diabetes. She is setting up a website for the public to design their own trials.

• Medical research >> Clinical Trials >> Organising trials >> Sir Richard Doll - Interview 31 >> Sir Richard Doll, a pioneer of clinical trials, explains an early attempt to run a randomised trial with wounded soldiers during WWII, and the lack of

Sir Richard Doll was one of the doctors who first demonstrated the link between lung cancer and smoking. He was Warden of Green College, Oxford. He was interviewed shortly before his death, in 2005.

• Medical research >> Clinical Trials >> Organising trials >> Lester - Interview 06 >> It takes a long time for most trial results to be published. Sometimes when results seem disappointing, researchers may want to carry on, hoping a tre

Lester’s son Ellis died in 2001 of variant CJD. Lester later became involved as a lay chair of a trial looking at the effectiveness of a drug called quinacrine for people with variant CJD.

• Medical research >> Clinical Trials >> Long term conditions >> Angela - Interview 23 >> Angela feels acupuncture has worked for her, but we need proper research into complementary therapies. At present we don’t have enough evidence whethe

Angela was diagnosed with Parkinson’s disease after taking part in a trial on nerve conduction. She has since been in a randomised trial of different drugs for Parkinson’s and would happily take part in another trial, despite having had side effects.(Angela is also on our Parkinson’s disease site, Interview 10).

• Medical research >> Clinical Trials >> Not taking part in a trial >> Polly - Interview 09 >> Polly believes we need more evidence about the effect of alternative therapies. The NHS is under pressure to provide them because people like them, bu

Polly was invited to be in a trial comparing tamoxifen against a placebo for breast cancer in the 1990s. She decided not to take part, because she felt there was already good evidence to support the use of tamoxifen.

• Medical research >> Clinical Trials >> Cancer drugs and radiotherapy - randomised trials >> Jayne - Interview 03 >> Jayne is in favour of more trials in surgery and her own field (dentistry), but explains why it is more complex when the outcome of treatment is depen

Jayne had breast cancer aged 33. She wanted to join a clinical trial but her consultant was not interested, so she transferred to another hospital and took part in a trial comparing tamoxifen with tamoxifen plus goserelin (Zoladex).

• Medical research >> Clinical Trials >> Long term conditions >> Angela - Interview 23 >> Angela would like more research into the causes of Parkinson’s. People put forward various theories in online forums, but it's important to distinguis

Angela was diagnosed with Parkinson’s disease after taking part in a trial on nerve conduction. She has since been in a randomised trial of different drugs for Parkinson’s and would happily take part in another trial, despite having had side effects.(Angela is also on our Parkinson’s disease site, Interview 10).

• Medical research >> Clinical Trials >> Screening, prevention other medical interventions >> Amanda - Interview 22 >> Amanda has worked on reviews of evidence about medical treatments, and is still shocked sometimes to find out how little evidence we have for some thi

Amanda has taken part in a trial of pro-biotic yoghurt for irritable bowel syndrome, and withdrew from a trial about early interventions to prevent diabetes. She is setting up a website for the public to design their own trials.

• Medical research >> Clinical Trials >> Long term conditions >> Angela - Interview 23 >> Angela would take part in a trial another time, including a placebo-controlled trial, because she feels it’s important for medical science.

Angela was diagnosed with Parkinson’s disease after taking part in a trial on nerve conduction. She has since been in a randomised trial of different drugs for Parkinson’s and would happily take part in another trial, despite having had side effects.(Angela is also on our Parkinson’s disease site, Interview 10).