Published: September 2011 Review date: Under review
We interviewed 40 people who are of Ashkenazi Jewish descent, and have a health condition that has a higher than average prevalence among people from this population. The genetic basis of some of these conditions, such as Tay Sachs and Familial Dysautonomia, has been identified, while others, such as Crohn’s disease and Factor 11 Deficiency have no identified genetic basis but are of a higher prevalence among Ashkenazi Jewish people. While at least 20 conditions have been found to be of particular relevance to people of Ashkenazi Jewish descent, we anticipate that more disorders will be identified in the future.
The prevalence of these conditions among the Ashkenazi Jewish population is commonly held to be consequence of two processes; founder effect and genetic drift. To find out more about these processes, and full descriptions of the conditions that people talk about on this site, please visit www.jewishgeneticdisordersuk.org.
We have not included experiences of all the conditions here as many of these conditions are rare, but we hope to add more experiences to this resource over time. To share in people’s experiences of ‘Jewish conditions’, click on the links below.