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• Nerves & brain >> Motor Neurone Disease >> ALS- amyotrophic lateral sclerosis/MND aged 50-64 >> Peter - Interview 38 >> He doesn't get too tired unless it's a very busy day, but he gets uncomfortable sitting in a wheelchair for too long. Lying in bed helps ease the disc

Peter was diagnosed three years ago (2004). Symptoms started in his arms and hands, and progressed to his legs. He now uses a wheelchair full-time.

• Nerves & brain >> Motor Neurone Disease >> Carers >> Roger & Luise - Interview 45 >> His wife got very tired but found it difficult to get comfortable in bed. Using different mattresses and cushions made little difference.

Roger's wife Luise was diagnosed in 2004 aged 59, after a year of weakness in her fingers and leg. Roger and his sons cared for Luise at home until her death in 2006.

• Nerves & brain >> Motor Neurone Disease >> Rarer forms - familial/inherited >> Liz - Interview 39 >> Pressure on her heels was uncomfortable at night, but a ROHO cushioned insert helped a lot. Getting a good night's sleep helps her cope better in the

Liz was diagnosed with inherited form of MND in 2004. (Her father and uncle both had MND). Weakness in her legs progressed to her arms; she is now in a wheelchair. Her speech is unaffected.

• Nerves & brain >> Motor Neurone Disease >> Rarer forms - PLS (primary lateral sclerosis) >> 'Speedy' - Interview 19 >> Tiredness is like a veil coming down. She gets so exhausted if she tries to do more than one thing a day that she feels physically almost uncomfortabl

'Speedy' was diagnosed with primary lateral sclerosis (PLS) nearly 2 years ago (in 2005) after 2 years of increasing leg weakness. She now uses a wheelchair and a hand-operated car.

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• Nerves & brain >> Motor Neurone Disease >> Tiredness, pain and discomfort >> Tiredness, pain and discomfort

Tiredness, pain and discomfort