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• Bones & joints >> Rheumatoid Arthritis >> Disease duration 16-20 years >> Melissa - Interview 50 >> She has tried Enbrel and Humira but both drugs are not longer effective on her RA. At the time of the interview she was due to start on influximab.

Melissa was first diagnosed with juvenile idiopathic arthritis and later with rheumatoid arthritis. She was on Methotrexate for about eight years. She has been on two Anti-TNF treatments: etanercepts (Enbrel) and adalimumab (Humira) and expects to be started on influximab soon.

• Bones & joints >> Rheumatoid Arthritis >> Disease duration 11-15 years >> Michelle - Interview 51 >> She explains that her anti-TNF drug is working well and that at present she prefers drug therapy to surgery because she is moving to France. Ankle dam

Michelle is currently on anti-TNF treatment: Humira. She has taken Methotrexate for a number of years but has had breaks in between following a biopsy that revealed liver scarring. Michelle was diagnosed with osteopenia (a milder form of osteoporosis) in her spine and needs to take calcium tablets regularly.

• Bones & joints >> Rheumatoid Arthritis >> Interview 58 >> Professor Moots talks about the limitations of anti-TNF therapy.

Robert Moots, Professor of Rheumatology, School of Clinical Sciences at the University of Liverpool and Consultant Rheumatologist at University Hospital Aintree, Liverpool.

• Bones & joints >> Rheumatoid Arthritis >> Disease duration 0-5 years >> Kate - Interview 52 >> Says that the benefits of her treatment outweigh any concerns she might have about side effects because she didn't have “much of a life anyway”.

None of her previous non-biologic treatments have worked long-term. Her condition deteriorated to such an extent that she was housebound and needed help with most things. Currently she is on Enbrel and Methotrexate and her condition is much improved.

• Bones & joints >> Rheumatoid Arthritis >> Disease duration 0-5 years >> Kate - Interview 52 >> She was almost housebound because of her RA. Doctors started her on etanercept (Enbrel) and provided the necessary information but did not promise any

None of her previous non-biologic treatments have worked long-term. Her condition deteriorated to such an extent that she was housebound and needed help with most things. Currently she is on Enbrel and Methotrexate and her condition is much improved.

• Bones & joints >> Rheumatoid Arthritis >> Interview 58 >> Professor Robert Moots explains about biologic treatments for rheumatoid arthritis.

Robert Moots, Professor of Rheumatology, School of Clinical Sciences at the University of Liverpool and Consultant Rheumatologist at University Hospital Aintree, Liverpool.

• Bones & joints >> Rheumatoid Arthritis >> Disease duration 0-5 years >> Kate - Interview 52 >> She was almost housebound because of her RA. Doctors started her on etanercept (Enbrel) and provided the necessary information but did not promise any

None of her previous non-biologic treatments have worked long-term. Her condition deteriorated to such an extent that she was housebound and needed help with most things. Currently she is on Enbrel and Methotrexate and her condition is much improved.

• Bones & joints >> Rheumatoid Arthritis >> Disease duration 0-5 years >> Kate - Interview 52 >> Talks about her hospital appointments, including her anti-TNF clinic and the type of tests she has done. She says that there is a lot of monitoring be

None of her previous non-biologic treatments have worked long-term. Her condition deteriorated to such an extent that she was housebound and needed help with most things. Currently she is on Enbrel and Methotrexate and her condition is much improved.

• Bones & joints >> Rheumatoid Arthritis >> Interview 58 >> Professor Robert Moots advices and informs about biologic drugs and pregnancy.

Robert Moots, Professor of Rheumatology, School of Clinical Sciences at the University of Liverpool and Consultant Rheumatologist at University Hospital Aintree, Liverpool.

• Bones & joints >> Rheumatoid Arthritis >> Disease duration 0-5 years >> Kate - Interview 52 >> At every opportunity, her consultant raises the issue of the importance of not getting pregnant while on Enbrel. She and her husband have decided not

None of her previous non-biologic treatments have worked long-term. Her condition deteriorated to such an extent that she was housebound and needed help with most things. Currently she is on Enbrel and Methotrexate and her condition is much improved.

• Bones & joints >> Rheumatoid Arthritis >> Disease duration 0-5 years >> Kate - Interview 52 >> At every opportunity, her consultant raises the issue of the importance of not getting pregnant while on Enbrel. She and her husband have decided not

None of her previous non-biologic treatments have worked long-term. Her condition deteriorated to such an extent that she was housebound and needed help with most things. Currently she is on Enbrel and Methotrexate and her condition is much improved.

• Bones & joints >> Rheumatoid Arthritis >> Disease duration 6-10 years >> Tara - Interview 53 >> She was 'amazed' to be given lots of information and advice about her anti-TNF medication. Says that she put her concerns about side effects of Humira

Following her diagnosis Tara was put on Methotrexate and this controlled her illness very well. She came off Methotrexate after deciding to have a second child. She describes her antenatal care as 'excellent' and felt safe and reassured. She is currently on anti-TNF treatment: Humira.

• Bones & joints >> Rheumatoid Arthritis >> Disease duration 6-10 years >> Tara - Interview 53 >> Talks about why they changed her medication to an anti-TNF treatment and the changes it has made to her quality of life.

Following her diagnosis Tara was put on Methotrexate and this controlled her illness very well. She came off Methotrexate after deciding to have a second child. She describes her antenatal care as 'excellent' and felt safe and reassured. She is currently on anti-TNF treatment: Humira.

• Bones & joints >> Rheumatoid Arthritis >> Disease duration 11-15 years >> Sarah - Interview 54 >> Says that she has a more positive outlook on life since starting on Enbrel because she knows her RA is under control and talks about what she is able

Until two years ago Sarah had very bad arthritis and was in severe pain. Her consultant applied and was granted funding to put her on anti-TNF treatment: Enbrel. Sarah describes Enbrel as 'completely and totally changing her life'.

• Bones & joints >> Rheumatoid Arthritis >> Disease duration 11-15 years >> Sarah - Interview 54 >> She couldn't cope with the side effects of methotrexate and stopped taking it. One of her consultants accepted her decision but another warned her tha

Until two years ago Sarah had very bad arthritis and was in severe pain. Her consultant applied and was granted funding to put her on anti-TNF treatment: Enbrel. Sarah describes Enbrel as 'completely and totally changing her life'.

• Bones & joints >> Rheumatoid Arthritis >> Disease duration 0-5 years >> Georgina - Interview 57 >> She started on B-cell therapy rituximab in October 2007. Previously she has tried two anti-TNF drugs. She has noticed some improvement in her conditio

Diagnosed two years ago Georgina has been on B-cell therapy rituximab since November 2007. Previously she was on anti-TNF therapies; Humira and Enbrel. Her diagnosis of RA came about after her Pain Syndrome consultant referred her to the rheumatology clinic.